4-amino-2-(trifluoromethyl)benzonitrile
Used as an intermediate in the drug bicalutamide; used for the preparation of phenyl derivatives as non-steroidal androgen receptor modulators.
Overview
4-Amino-2-(trifluoromethyl)benzonitrile is an organic and pharmaceutical intermediate. It serves as a building block for kinase inhibitors and anticancer agents via condensation and cyclization reactions, targeting cancer therapies.
Synonyms: 5-AMINO-2-CYANOBENZOTRIFLUORIDE; BUTTPARK22\01-63;2-CYANO-5-AMINOBENZOTRIFLUORIDE; 4-CYANO-3-TRIFLUOROMETHYLANILINE; 4-AMINO-2-TRIFLUOROMETHYLBENZONITRILE; 5-AMINO-2-CYANOBENZOTRIFLUORID; 4-Amino-2-(trifluoromethyl)benzontrile; 4-Bromo-2-TrifluoromethylAniline/4-Bromo-2-(Trifluoromethyl)Aniline/2-Amino-5-Bromobenzotrifluoride
EINECS: 000-000-0
Product Categories: Aromatic Hydrocarbons; Organic Building Blocks; Chemicalintermediate for Bicalutamide; Aromatic Nitriles; Aromatic Halides(substituted); Phenyls&Phenyl-Het; Aniline; Bicalutamide; Amines; Aromatics
Mol File: 654-70-6.mol
Physicochemical Properties
Melting point: 141-145 °C(lit.)
Boiling point: 294.5±40.0 °C(Predicted)
Storage condition: Keep in dark place,Sealed in dry,Room Temperature
Solubility: DMSO (slightly), methanol (slightly)
Form: Powder
Color: White to Off-white