TM-5614

TM-5614•Dermatology

CAS: 1190221-46-5

MF: C21H17ClN2O6

MW: 428.82

Indications

Chronic myeloid leukemia; Non-small cell lung cancer; Melanoma; Interstitial lung disease; Novel coronavirus infection; Angiosarcoma

Therapeutic Target

PAI-1

Usage

A selective plasmin inhibitor that significantly reduces prostaglandin D2 (PGD2) levels, which are strongly associated with androgenetic alopecia (AGA); suitable for scalp serums and hair growth tonics targeting androgenetic alopecia.

Specification

＞99%

Product Description

Overview

TM-5614 is an innovative PAI-1 (Plasminogen Activator Inhibitor-1) inhibitor renowned for its potent anti-fibrotic properties and ability to reverse follicle miniaturization, hailed in communities as a “multi-functional anti-aging and hair growth ingredient.” Although officially developed for anti-aging and cancer treatments, by inhibiting PAI-1 activity, it effectively alleviates scalp fibrosis, restores a healthy follicle environment, and promotes hair growth along with gray hair reversal. Its core benefits include significantly reducing perifollicular fibrosis, reversing follicle miniaturization, providing antioxidant protection to delay follicular aging, and demonstrating gray hair reduction in community applications. Widely used in community-sourced hair growth serums, scalp care tonics, and anti-hair loss products.

Synonyms: TM5614; RS-5614; RS5614; Benzoic Acid

Product Categories: Plasminogen Activator Inhibitor-1 Inhibitors (PAI-1 Inhibitors); Anti-Fibrotic Agents; Scalp Microenvironment Repair Agents

Mol File: 1190221-46-5.mol