
Capixyl
Inhibits 5α-reductase, reduces DHT, strengthens follicle anchoring, reduces inflammation, and promotes ECM regeneration; suitable for shampoos, conditioners, and daily scalp care products.
Overview
Capixyl is a star patented complex celebrated for its golden combination of Acetyl Tetrapeptide-3 and high-purity red clover extract, known as “the most comprehensive daily anti-hair loss and hair-preserving ingredient.” Through multi-targeted mechanisms, it simultaneously inhibits 5α-reductase, reduces DHT damage, strengthens follicle anchorage, and promotes extracellular matrix regeneration, comprehensively combating follicle miniaturization and fibrosis. Its core benefits include significantly reducing hair loss, reinforcing root stability, stimulating new hair growth, and being gentle with long-lasting effects. Extensively used in daily shampoos, conditioners, scalp serums, and anti-hair loss sprays.
Synonyms: AcetylTetrapeptide-3; Ac-KGHK; AcetylTetrapeptide-3/Capixyl-3; L-Lysinamide,N2-acetyl-L-lysylglycyl-L-histidyl-
EINECS: 1308068-626-2
Product Categories: Botanical Complex; 5α-Reductase Inhibitors; Peptide & Triterpenoid Combinations; Extracellular Matrix Regenerators; Anti-Inflammatory & Anti-Androgen Complexes; Polypeptides; Hair Growth Peptides; Anti-aging; Cosmetic Raw Materials; Beauty Peptides
Mol File: 827306-88-7.mol
Physicochemical Properties
Boiling point: 1075.4±65.0 °C(Predicted)
Density: 1.250±0.06 g/cm3(Predicted)
Storage temp.: Keep in dark place,Inert atmosphere,Store in freezer, under -20°C
Solubility: DMF: 14 mg/ml DMSO: 10 mg/ml Ethanol: 10 mg/ml PBS (pH 7.2): 10 mg/ml
Form: Solid
Color: Off-white to light yellow
MSDS Information
Experimental Data
1.Cell Experiment
Solubility in H2O: 116.67 mg/mL (228.94 mM; assisted by ultrasonication)
Preparing Stock Solutions:

Please select a suitable solvent to prepare the stock solution based on the solubility of the product in different solvents. Once the solution is prepared, divide it into aliquots for storage to avoid product degradation caused by repeated freezing and thawing.
Storage conditions and shelf life for the stock solution: -80°C, 6 months; -20°C, 1 month (store sealed, away from moisture). When stored at -80°C, use within 6 months; when stored at -20°C, use within 1 month.
* Note: If you choose water as the stock solution, dilute it to the working solution and then filter-sterilize with a 0.22 μm membrane before use.
Pharmacodynamics
Mechanism Of Action
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